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Peer-reviewed veterinary case report

Recombinant vaccines for pets - safety and benefits

By Van Kampen, K R·Published in The Veterinary clinics of North America. Small animal practice·2001·Van Kampen Group, United States·View original on PubMed

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Original publication title: Recombinant vaccine technology in veterinary medicine.

Plain-English summary

Recombinant vaccine technology is a newer approach in veterinary medicine that offers several advantages. These vaccines are designed to be safe and effective without exposing pets to the actual disease-causing germs. They don't require extra substances to boost their effectiveness and can often be stored at room temperature, making them easier to handle. Some of the vaccines developed using this technology protect against diseases like Lyme disease, rabies, and canine distemper, among others. Overall, this technology provides a promising way to keep pets healthy with fewer risks.

Abstract

Recombinant technology is relatively new to veterinary medicine. It combines safety, purity, potency, and efficacy in the vaccine. Its positive features include not exposing the vaccinate to the pathogen, the lack of need for adjuvants, and stability that allows some vaccine to remain viable at ambient temperatures. These recombinants can receive multiple genetic inserts and present an opportunity to have multiple combination vaccines for use in animals. Licensed recombinant vaccines in veterinary medicine include those protecting against Lyme disease, pseudorabies, rabies, canine distemper, Newcastle disease, and a strain of avian influenza.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11446102/