Peer-reviewed veterinary case report
Recording EMT Activity by Lineage Tracing during Metastasis.
- Journal:
- Developmental cell
- Year:
- 2020
- Authors:
- Vieugué, Pauline & Blanpain, Cédric
- Affiliation:
- Laboratory of Stem Cells and Cancer
Abstract
In this issue of Developmental Cell, Li et al. develop a novel lineage tracing system to record EMT activity during lung metastasis of mammary tumors. Using EMT-tracer mouse models, they reveal that N-cadherin is transiently expressed by most metastasis-initiating cells and demonstrate its functional importance during the metastatic cascade.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/32931747/