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Peer-reviewed veterinary case report

Recurrent Myxoid Liposarcoma of the Upper Thoracic Spine: A Case Report.

Year:
2025
Authors:
Lin H et al.
Affiliation:
Orthopedics Department · China

Abstract

<h4>Introduction</h4>Liposarcoma, one of the most common soft tissue sarcomas, originates from primitive mesenchymal cells. However, spinal involvement of liposarcoma, whether primary or metastatic, is rare. According to literature reports, myxoid/round cell liposarcomas are the most common types affecting the spine. Spinal liposarcomas, whether primary or metastatic, have only been sporadically reported.<h4>Case presentation</h4>The author presents an unusual case of recurrent myxoid liposarcoma originating from the erector spinae muscle, infiltrating the upper thoracic spine in a 65-year-old female. The patient presented with a 1-week history of progressively worsening right chest and back pain. The treatment approach involved surgical intervention with wide tumor resection, spinal cord decompression, posterior instrumentation, and thoracoplasty, complemented by radiotherapy.<h4>Conclusion</h4>The preferred treatment is en bloc resection with wide margins. Postoperative radiation therapy can serve as complementary treatment for piecemeal resection. A follow-up is necessary because of the potential for recurrence.

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Original publication: https://europepmc.org/article/MED/39980528