Peer-reviewed veterinary case report
Reference systems for the determination of 10B through autoradiography images: application to a melanoma experimental model.
- Journal:
- Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
- Year:
- 2011
- Authors:
- Portu, A et al.
- Affiliation:
- Centro Ató
- Species:
- rodent
Abstract
The amount of (10)B in tissue samples may be determined by measuring the track density in the autoradiography image produced on a nuclear track detector. Different systems were evaluated as reference standards to be used for a quantitative evaluation of boron concentration. The obtained calibration curves were applied to evaluate the concentration of (10)B in melanoma tumour of NIH nude mice after a biodistribution study. The histological features observed in the tissue sections were accurately reproduced by the autoradiography images.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21419638/