Peer-reviewed veterinary case report
Venous blood clot shrank after pituitary surgery in dog
By Tanaka, S et al.·Published in The Journal of small animal practice·2023·Faculty of Veterinary Science, Japan·View original on PubMed →
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Original publication title: Regression of venous thrombus after trans-sphenoidal hypophysectomy for pituitary-dependent hyperadrenocorticism in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old male dachshund was brought in for surgery due to suspected pituitary-dependent hyperadrenocorticism (a hormone disorder) and a blood clot in the portal vein. Advanced imaging confirmed the presence of the clot and showed liver issues. After the dog underwent surgery to remove the pituitary mass, he continued taking blood-thinning medications. Six months later, follow-up tests showed that the blood clot had completely disappeared, suggesting that the treatment may have been effective.
People also search for: dog blood clot treatment · dachshund pituitary gland surgery · hyperadrenocorticism symptoms in dogs
Abstract
An 8.0-kg 8-year-old male dachshund was presented for surgical treatment of suspected pituitary-dependent hyperadrenocorticism with portal vein thrombosis. Advanced diagnostic imaging revealed a thrombus in the splenic and portal veins. For the portal vein thrombus, CT angiography showed an enhanced timing delay in the lateral right and caudate liver lobes. Blood tests showed a marked increase in the liver panel, including total bile acid. Brain MRI revealed a pituitary mass, suggesting pituitary-dependent hyperadrenocorticism. The mass was completely resected. The preoperative antithrombotic therapy of rivaroxaban (0.66 mg/kg, PO, once per day) and clopidogrel sulphate (1.66 mg/kg, PO, once per day) was continued postoperatively. Six months after resection of the pituitary mass, the thrombus had disappeared. Further studies are required to prove a causal association between the disappearance of the thrombus and the treatments provided.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36335913/