Peer-reviewed veterinary case report
Dog survival and surgery success by mast cell tumor grade
By Murphy, S et al.·Published in The Veterinary record·2004·Centre for Preventive Medicine·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Relationships between the histological grade of cutaneous mast cell tumours in dogs, their survival and the efficacy of surgical resection.
- Species:
- dog
Plain-English summary
A study looked at 340 skin tumors called mast cell tumors in 280 dogs to see how their grade affected survival and treatment success. Dogs with well-differentiated tumors had a 100% survival rate after one year, while those with poorly differentiated tumors had only a 46% survival rate, living an average of just 278 days. The research found that even with complete surgical margins, some tumors still regrew, but dogs with well-differentiated tumors did well overall. This suggests that the type of tumor is important for predicting outcomes after surgery.
People also search for: dog mast cell tumor survival rate · dog skin tumor treatment · what is a mast cell tumor in dogs
Abstract
The histological grade of 340 cutaneous mast cell tumours derived from 280 dogs was determined by an established histological grading system; 87 of the tumours (26 per cent) were well differentiated, 199 (59 per cent) were intermediately differentiated and 54 (16 per cent) were poorly differentiated. The one-year survival rates for the dogs with tumours of these three grades were significantly different (P = 0.0001), being 100 per cent, 92 per cent and 46 per cent, respectively. The median survival time for the dogs with poorly differentiated tumours was 278 days, significantly shorter than that for the dogs with either intermediately or well-differentiated tumours, which were both over 1300 days. Regrowth of the tumours was identified in 10 (19 per cent) of the dogs with poorly differentiated tumours, 12 (6 per cent) of the dogs with intermediately differentiated tumours and one of the dogs with well-differentiated tumours; only three of the tumours which regrew had initially had complete margins. The results suggest that wide surgical margins are not a prerequisite for a successful long-term outcome in dogs with well-differentiated cutaneous mast cell tumours.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15224593/