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Peer-reviewed veterinary case report

Dog with kidney failure and amyloidosis caused by Ehrlichia canis

By Luckschander, N et al.·Published in Schweizer Archiv fur Tierheilkunde·2003·Abteilung Innere Medizin der Kleintiere·View original on PubMed

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Original publication title: [Renal amyloidosis caused by Ehrlichia canis].

Species:
dog

Plain-English summary

An 8-year-old female Old English Sheepdog was brought to the vet because she was very tired and had been losing weight for a year. She also had recurring fevers and some swollen lymph nodes. Tests showed she had a tick-borne infection called Ehrlichiosis, which led to kidney problems due to a condition called amyloidosis. Unfortunately, this means her kidneys were not functioning properly. The vet suspected that the Ehrlichiosis caused the kidney issues, and further treatment would be necessary to manage her health.

People also search for: dog lethargy and weight loss · Old English Sheepdog kidney disease · Ehrlichiosis treatment in dogs

Abstract

An 8 year old, intact female, Old English Sheepdog was presented with lethargy and chronic weight loss of one year duration. The dog suffered from recurrent fever and a mild peripheral lymphadenopathy. Mild thrombocytopenia, monoclonal hyperglobulinemia and positive Ehrlichia canis antibody titer were indicative of Ehrlichiosis. The patient developed proteinuria and renal failure, which suggested the presence of glomerulopathy. Immunohistochemical staining of renal biopsy specimen demonstrated AA amyloidosis. Chronic ehrlichiosis was suspected to be the cause of the dog's renal amyloidosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14593934/