Peer-reviewed veterinary case report
Renal dysfunction in a case of purpura haemorrhagica in a horse.
- Journal:
- The Veterinary record
- Year:
- 1982
- Authors:
- Roberts, M C & Kelly, W R
- Species:
- horse
Plain-English summary
A four-year-old thoroughbred horse was brought in because it was showing signs of purpura haemorrhagica, which is a condition that causes bleeding under the skin. During the examination, the veterinarians found that the horse also had kidney problems, indicated by a lot of protein in its urine and high levels of waste products in the blood. These kidney issues might have gotten worse due to treatment with diuretics, which help remove excess fluid. An autopsy showed that the horse had specific types of kidney inflammation and also chronic inflammation in the chest area. It seems that immune complexes in the horse's body may have caused both the kidney problems and the bleeding condition.
Abstract
A four-year-old thoroughbred was presented with clinical manifestations of purpura haemorrhagica. Evidence of renal involvement consistent with glomerulopathy and nephrotic syndrome, characterised by heavy proteinuria and azotaemia, became apparent and may have been exacerbated by diuretic therapy. Autopsy revealed membrano- and mesangial proliferative glomerulonephritis and chronic pleuritis. Circulating immune complexes may have been responsible for the renal diseases and the purpura.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/7199777/