Peer-reviewed veterinary case report
Kidney tumor signs and diagnosis in a 17-year-old Maltese dog
By Cho, Seung-Hee et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2020·Department of Veterinary Pathology, South Korea·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Renal interstitial cell tumor in a dog: clinicopathologic, imaging, and histologic features.
- Species:
- dog
Plain-English summary
A 17-year-old spayed female Maltese was brought to the vet with a mass in her right abdomen, along with signs of kidney problems and anemia. Imaging showed that her right kidney was enlarged due to a mass that had some mineralization. After surgery, the mass was found to be a renal interstitial cell tumor, which had some malignant features. While these tumors are usually benign, this case showed that they can sometimes be more serious. The vet may use specific tests to help diagnose similar tumors in the future.
People also search for: dog abdominal mass · Maltese kidney tumor · renal interstitial cell tumor in dogs · dog kidney disease symptoms
Abstract
Renal interstitial cell tumors are benign tumors of renomedullary origin; however, malignant features have not been reported in dogs, to our knowledge. A 17-y-old spayed female Maltese dog was presented to a local animal hospital with a mass in the right abdomen. Clinicopathologic findings prior to surgery revealed renal insufficiency and anemia. Imaging revealed that the right kidney was enlarged by an amorphous mass with opaque areas, indicative of mineralization. Upon histologic examination, the mass was comprised of malignant mesenchymal cells that produced mucinous matrix. The tumor cells were positive for vimentin and COX-2, but negative for pancytokeratin; the matrix stained positively with alcian blue. Therefore, the mass was diagnosed as a renal interstitial cell tumor, with malignant features. COX-2 may be useful in the diagnosis of canine renal interstitial cell tumors, similar to its diagnostic role in humans.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31876249/