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Peer-reviewed veterinary case report

Renal medullary rim sign in 2 adult quarter horses.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
1998
Authors:
Ramirez, S et al.
Affiliation:
Department of Veterinary Clinical Sciences · United States
Species:
horse

Plain-English summary

This report talks about a specific ultrasound finding called the renal medullary rim sign in two adult quarter horses. This sign was linked to issues caused by either long-term or sudden high doses of a medication called phenylbutazone, which is often used for pain relief in horses. While this ultrasound finding has been seen before, it was only noted in young foals given large amounts of the drug in a controlled setting. The outcome of the cases wasn't detailed, but it highlights a potential risk of using this medication in adult horses.

Abstract

This report describes a renal ultrasonographic abnormality (medullary rim sign), which was identified in 2 separate cases of spontaneously occurring disease associated with chronic and acute overdosage of phenylbutazone therapy. In horses, medullary rim sign has only been documented in neonatal foals experimentally administered large doses of phenylbutazone.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/9789678/