Peer-reviewed veterinary case report
Replicon particle vaccine protects swine against influenza.
- Journal:
- Comparative immunology, microbiology and infectious diseases
- Year:
- 2010
- Authors:
- Bosworth, B et al.
- Affiliation:
- Department of Animal Science · United States
Abstract
An alphavirus derived replicon particle (RP) vaccine expressing the cluster IV H3N2 swine influenza virus (SIV) hemagglutinin (HA) gene induced protective immunity against homologous influenza virus challenge. However, pigs with maternal antibody had no protective immunity against challenge after vaccination with RP vaccines expressing HA gene alone or in combination with nucleoprotein gene.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21094422/