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Peer-reviewed veterinary case report

Research advances in dysphagia animal models.

Journal:
Animal models and experimental medicine
Year:
2025
Authors:
Bai, Junhui et al.
Affiliation:
Department of Rehabilitation · China
Species:
dog

Abstract

Dysphagia is a common complication of stroke, Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). The construction of animal models of dysphagia is an important way to explore its pathogenesis and treatment. At present, the animal models of dysphagia mainly include rodents, nonhuman primates, and other mammals, such as pigs and dogs. This review systematically summarizes the establishment and evaluation of dysphagia animal models in stroke, PD, and ALS in three kinds of experimental animals, providing a basis for the selection of appropriate animal models of dysphagia.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/40566744/