Research on Postoperative Scar Quality of Sutures and Skin Surface Adhesives.

Abstract

<h4>Objectives</h4>This study aimed to compare the quality of scarring of DERMABOND PRINEO (Ethicon, Inc., Somerville, NJ, USA)^Ⓡ by conducting a half-side test on the same wound to determine its superiority. If the utility of DERMABOND PRINEO^Ⓡ is established, its use can be expanded for more cases and higher quality medical care can be provided.<h4>Methods</h4>Patients who underwent two-stage breast reconstruction were included. The first surgery was half closed with DERMABOND PRINEO^Ⓡ and nylon threads, and the time was measured. At the second surgery, all scars were removed, and a histopathological examination was done. Scars were evaluated with the Vancouver Scar Scale (VSS) and visual analogue scale (VAS), and statistical analysis was performed.<h4>Results</h4>Time to closure was significantly shorter in the DERMABOND PRINEO^Ⓡ group. Postoperative VSS scores for pliability were significantly lower in the suture group, and the total VSS score was significantly lower in the suture group from 3 to 6 months postoperatively. Patients rated postoperative wound pain, itching, appearance, and satisfaction with the VAS, but no significant differences were observed between the two groups. The scars were compared with hematoxylin-eosin staining and Elastica van Gieson staining. Differences were seen in the increase of elastic fibers in the dermal reticular layer, a characteristic difference between the two groups.<h4>Conclusions</h4>The use of DERMABOND PRINEO^Ⓡ leads to a reduction in operative time and impacts the maturity of the scar. It is expected that the indications for DERMABOND PRINEO^Ⓡ can be further expanded in the future.