Peer-reviewed veterinary case report
Effect of androgen hormone treatment on dog skin glands
By Gâjâilă, G et al.·Published in Polish journal of veterinary sciences·2022·Faculty of Veterinary Medicine·View original on PubMed →
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Original publication title: Research on the effect of an androgenic hormone product on the functional status of common sebaceous glands in dogs.
- Species:
- dog
Plain-English summary
A study looked at how a hormone treatment called Anabolin forte affected the skin glands in dogs, which can be linked to skin tumors. The researchers treated both male and female dogs with this hormone for two days and measured the amount of oil (sebum) their skin produced and the skin's pH level. They found that the hormone increased oil production and lowered the skin's pH in both male and female dogs compared to those that didn't receive the treatment. This suggests that the hormone may influence skin health in dogs, which could be important for preventing skin tumors.
People also search for: dog skin tumors treatment · hormone therapy for dogs · sebaceous gland issues in dogs
Abstract
Nowadays, a high incidence of cutaneous tumors is observed in domestic carnivorous in pet clinic, the sebaceous glands being the starting point for the development of these tumors. The hormonal imbalances are considered to be the most common etiology for these tumors, so the current research is based on the effects of an androgenic like hormonal drug on the functionality of the sebaceous glands in dogs. For this purpose, 32 dogs were distributed in 4 groups: control group 1 (8 dogs - females), control group 2 (8 dogs - males), experimental group 1 (8 dogs - females) and experimental group 2 (8 dogs - males). The investigation targeted the pH of skin and the rate of sebum's secretion. The animals from the experimental groups were treated with Anabolin forte for 2 days at a dose of 1 mg/kg body weight/day, intramuscular. The obtained results revealed that administration of Anabolin forte in males induced a significantly distinct intensification (with 10.66%) of sebum's secretion and a significant decrease of pH of the skin (with 17.1%) compared to the animals from the control group. The administration of Anabolin forte in females induced a significantly distinct intensification (with 17.47%) of sebum's secretion and a significant decrease of the pH of the skin (with 14.32%) compared to the animals from the control group.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36156608/