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Peer-reviewed veterinary case report

Resolution of superficial necrolytic dermatitis following excision of a glucagon-secreting pancreatic neoplasm in a dog.

Journal:
Journal of the American Animal Hospital Association
Year:
1997
Authors:
Torres, S M et al.
Affiliation:
Department of Small Animal Clinical Sciences · United States
Species:
dog

Abstract

An 11-year-old, neutered male standard poodle was diagnosed with superficial necrolytic dermatitis and a glucagon-secreting pancreatic islet neoplasm based on clinical, biochemical, histopathological, immunohistochemical, and hormonal findings. Hyperglucagonemia, hyperinsulinemia, and hypoaminoacidemia were observed on preoperative laboratory analysis. Abnormal laboratory values returned to normal, and complete resolution of skin lesions occurred after tumor excision. The dog has remained clinically normal for six months following surgery.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/9204466/