Peer-reviewed veterinary case report
How to evaluate treatment response for solid tumors in dogs
By Nguyen, S M et al.·Published in Veterinary and comparative oncology·2015·Department of Veterinary Biosciences, United States·View original on PubMed →
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Original publication title: Response evaluation criteria for solid tumours in dogs (v1.0): a Veterinary Cooperative Oncology Group (VCOG) consensus document.
- Species:
- dog
Plain-English summary
Currently, there isn't a standard way for veterinarians to measure how well treatments are working for dogs with solid tumors, which makes it hard to compare results from different therapies. A group of veterinary cancer specialists has come together to create a new guideline based on methods used in human medicine. This new guideline, called cRECIST v1.0, aims to provide clear and consistent procedures for evaluating treatment responses in dogs. The hope is that this will help veterinarians better understand and compare the effectiveness of various cancer treatments for pets. If adopted, this could improve care for dogs with cancer by making it easier to track how well they are responding to treatment.
Abstract
In veterinary medical oncology, there is currently no standardized protocol for assessing response to therapy in solid tumours. The lack of such a formalized guideline makes it challenging to critically compare outcome measures across various treatment protocols. The Veterinary Cooperative Oncology Group (VCOG) membership consensus document presented here is based on the recommendations of a subcommittee of American College of Veterinary Internal Medicine (ACVIM) board-certified veterinary oncologists. This consensus paper has used the human response evaluation criteria in solid tumours (RECIST v1.1) as a framework to establish standard procedures for response assessment in canine solid tumours that is meant to be easy to use, repeatable and applicable across a variety of clinical trial structures in veterinary oncology. It is hoped that this new canine RECIST (cRECIST v1.0) will be adopted within the veterinary oncology community and thereby facilitate the comparison of current and future treatment protocols used for companion animals with cancer.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23534501/