Peer-reviewed veterinary case report
How well azole antifungals treat cat sporotrichosis infections
By Pereira, S A et al.·Published in The Veterinary record·2010·Instituto de Pesquisa Clí, Brazil·View original on PubMed →
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Original publication title: Response to azolic antifungal agents for treating feline sporotrichosis.
- Species:
- cat
Plain-English summary
A group of 773 cats with sporotrichosis, a fungal infection, were treated with either ketoconazole or itraconazole to see which worked better. Out of these, about 31% showed improvement, with more cats responding to itraconazole than to ketoconazole. However, nearly 40% of the cats experienced side effects, and some either stopped treatment or were still being treated when the study ended. It's important for pet owners to discuss potential risks and benefits of these antifungal medications with their veterinarian.
People also search for: cat sporotrichosis treatment · ketoconazole side effects in cats · itraconazole for cat fungal infection
Abstract
The effectiveness and safety of treatment with ketoconazole and itraconazole were compared in 773 sporotrichosis-infected cats over a four-year period (2002 to 2005). Five hundred and ninety-eight cats received oral ketoconazole and 175 received oral itraconazole. Treatment was successful in 238 (30.8 per cent) cats, of which 171 (28.6 per cent) of 598 received 13.5 to 27.0 mg/kg/day ketoconazole and 67 (38.3 per cent) of 175 received 8.3 to 27.7 mg/kg/day itraconazole. Adverse effects were reported in 306 (39.6 per cent) of the cats, 105 (13.6 per cent) died and 430 (55.6 per cent) dropped out of treatment or were still under treatment at the time of data analysis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20208075/