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Peer-reviewed veterinary case report

Response to thyrotropin-releasing hormone (TRH) in a horse with hyperthyroidism associated with a functional thyroid adenoma.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2019
Authors:
Costello, Jillian et al.
Affiliation:
College of Veterinary Medicine · United States
Species:
horse

Plain-English summary

A 16-year-old American Paint Horse gelding was brought in because he was losing weight and had high levels of thyroid hormones due to a growth on his thyroid gland called a functional thyroid adenoma. When tested with a hormone stimulation test, he did not show the expected response, which indicated that his thyroid was not functioning properly. After the adenoma was surgically removed, the horse's clinical signs improved, and he returned to better health.

Abstract

A 16-year-old American Paint Horse gelding was presented for evaluation of weight loss and high serum thyroid hormone concentrations resulting from a functional thyroid adenoma. The horse showed no response to a thyrotropin-releasing hormone (TRH) stimulation test. Clinical signs resolved following surgical removal of the adenoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/31692666/