Peer-reviewed veterinary case report
Pulmonary valve narrowing returned after balloon treatment
By Sunahara, Hiroshi et al.·Published in The Journal of veterinary medical science·2015·Azabu University, Japan·View original on PubMed →
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Original publication title: Restenosis after balloon valvuloplasty in a dog with pulmonary stenosis.
- Species:
- dog
Plain-English summary
A 2-month-old female Chihuahua was diagnosed with severe pulmonary valve narrowing, known as pulmonary stenosis. She underwent a procedure called balloon valvuloplasty to help open the valve, which initially seemed successful. However, 19 months later, the valve narrowed again, leading to serious health issues. Unfortunately, the dog had to be euthanized during a surgical attempt to correct the problem when she was 5 years old. A postmortem examination showed that the valve had thickened significantly, which restricted its movement and caused the restenosis (re-narrowing).
People also search for: Chihuahua pulmonary stenosis treatment · dog heart valve surgery complications · balloon valvuloplasty in dogs
Abstract
A two-month-old female Chihuahua was diagnosed as severe pulmonary valvular stenosis (PS). Although balloon valvuloplasty (BV) was successfully performed, restenosis was observed 19 months after the procedure. Euthanasia was chosen due to low output syndrome during the surgical repair attempted when the dog was 5 years old. Postmortem examination revealed markedly thickened pulmonary valve due to the increase of extracellular matrix which might be produced by increased α smooth muscle actin-positive myofibroblasts. The thickening of the valve was associated with restriction of the valve's motion, resulting in restenosis in the present case. This is the first case report documented histopathological and immunohistochemical findings of the restenotic pulmonary valve in dogs with PS after BV.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25252640/