Peer-reviewed veterinary case report
High blood pressure in dogs with primary immune-mediated hemolytic
By Hall, Georgina B F et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2022·Hospital for Small Animals, United Kingdom·View original on PubMed →
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Original publication title: Retrospective evaluation of systemic hypertension in dogs with nonassociative (primary) immune-mediated hemolytic anemia (December 2016 to April 2019): 26 cases.
- Species:
- dog
Plain-English summary
A group of 26 dogs with immune-mediated hemolytic anemia (a condition where the immune system attacks red blood cells) was found to have high blood pressure, with half of them showing hypertension during their hospital stay. The average blood pressure in these dogs was significantly higher than in a control group of dogs with seizures. While many of the dogs experienced elevated blood pressure, it did not seem to affect their immediate survival. The findings suggest that monitoring blood pressure in dogs with this condition is important, as they may need treatment for hypertension.
People also search for: dog high blood pressure treatment · immune-mediated hemolytic anemia in dogs · signs of hypertension in dogs
Abstract
OBJECTIVE: To report the prevalence of arterial hypertension in a population of dogs with nonassociative immune-mediated hemolytic anemia (IMHA) on presentation and during hospitalization. To determine the relationships of systolic blood pressure (SBP) with mortality and a prognostic indicator, the canine hemolytic anemia objective score. DESIGN: Retrospective observational study (December 2016 to April 2019). SETTING: University teaching hospital. ANIMALS: Twenty-six clinical dogs presenting to the ICU with nonassociative (primary) IMHA and a control group of 23 clinical dogs with idiopathic epilepsy hospitalized in the ICU for seizure treatment or monitoring. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Hypertension was defined as SBP ≥ 160 mm Hg and severe hypertension as SBP ≥ 180 mm Hg. Mean SBP was significantly increased in IMHA dogs (161 mm Hg, SD = 21) compared to ICU control dogs (138 mm Hg, SD = 14; P < 0.005). Hypertension was present in 13 of 26 (50.0%) dogs across the period of hospitalization and was severe in three of 26 (11.5%). During at least 1 day of hospitalization, 18 of 26 (69.2%) dogs were hypertensive and eight of 26 (34.6%) were severely hypertensive. Hypertension was not associated with short-term mortality or canine hemolytic anemia objective score. CONCLUSIONS: In this retrospective study, hypertension was more prevalent in dogs with nonassociative IMHA than a control population of ICU-hospitalized dogs. An association between autoimmune conditions and hypertension has been previously reported in people but not within a canine population. Hypertension in dogs may have an inflammatory or autoimmune etiology. SBP should be monitored closely in canine IMHA, in case antihypertensive treatment is required.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35080103/