Peer-reviewed veterinary case report
Canine distemper prognosis linked to antibody levels in 2-4 month
By Kubo, Takuya et al.·Published in The Journal of veterinary medical science·2008·Department of Pathobiology, Japan·View original on PubMed →
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Original publication title: Retrospective serological analysis of spontaneous CDV infection in 192 dogs.
- Species:
- dog
Plain-English summary
A group of unvaccinated puppies, aged 2 to 4 months, were diagnosed with canine distemper virus (CDV) after tests confirmed the virus in their tonsils. Out of 192 dogs, 74 had high levels of antibodies that indicated a better chance of recovery, while 118 had low or no antibodies and faced a poor prognosis. The study suggests that measuring these antibody levels can help predict how well a dog will respond to CDV infection.
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Abstract
Spontaneous cases of canine distemper virus (CDV) infection were serologically evaluated. The 192 dogs in which CDV antigen was confirmed from tonsil by immunohistological examination were 2- to 4-months old, of various breeds, and unvaccinated. The prognoses were good in 74 dogs with significantly high levels of anti-CDV passive hemolytic aggregation (PHA) titer. In the other 118 dogs with poor prognoses, anti-CDV PHA titer was not detected. Anti-CDV PHA titer had the most significant association with the prognoses of CDV infection, and could be the most reliable and useful indicator for evaluating such prognoses.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18525169/