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Peer-reviewed veterinary case report

Surgery outcomes in 8 dogs with insulinoma and low blood sugar

By Madarame, Hiroo et al.·Published in The Journal of veterinary medical science·2009·Veterinary Teaching Hospital, Japan·View original on PubMed

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Original publication title: Retrospective study of canine insulinomas: eight cases (2005-2008).

Species:
dog

Plain-English summary

Eight dogs with insulinomas, a type of tumor that causes low blood sugar, were treated after showing symptoms like weakness and confusion. All dogs underwent surgery to remove the tumors, which was necessary due to their unique clinical signs and low blood sugar levels. However, blood tests for insulin levels were inconsistent, with some dogs showing normal levels despite having the disease. Despite these challenges in diagnosis, the surgical treatment was performed, and the dogs were monitored for recovery.

People also search for: dog insulinoma symptoms · low blood sugar in dogs · insulinoma treatment for dogs

Abstract

This retrospective study examined 8 cases of pathologically diagnosed insulinoma. Surgical intervention was performed in all cases, once insulinoma was suspected based on unique clinical signs, hypoglycemia, and/or findings on ultrasonography. At the same time, insulin and glucose concentrations were measured before surgery for clinical diagnosis. Although all cases displayed typical clinical signs and hypoglycemia, insulin concentrations varied with 3 of 8 cases showing levels within the reference interval. In addition, to confirm the reliability of measured values, we submitted serum samples from 4 cases to two commercial veterinary laboratories. Results differed considerably between laboratories, with no apparent correlations between the two. In Laboratory A, 3 of 4 cases were above the reference interval, and 1 case was in the middle of the reference interval. Conversely, in Laboratory B, 3 of 4 cases were above the reference interval, and 1 case was below the reference interval. Split decisions regarding the diagnosis of insulinoma were seen for 2 of the 4 cases.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19652477/