Peer-reviewed veterinary case report
Radiation treatment results for dogs with nasal tumors
By Maruo, Takuya et al.·Published in The Journal of veterinary medical science·2011·Veterinary Teaching Hospital, Japan·View original on PubMed →
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Original publication title: Retrospective study of canine nasal tumor treated with hypofractionated radiotherapy.
- Species:
- dog
Plain-English summary
A group of 63 dogs with nasal tumors received a special type of radiation therapy called hypofractionated multiportal radiation, which was divided into two parts. Most of the dogs showed improvement in their symptoms, with 84% responding positively to the treatment. The average survival time after treatment was about 197 days, with some dogs living much longer. Side effects were mostly mild, and only one dog developed a more serious issue a year later. This treatment approach may help minimize side effects for dogs with certain types of nasal tumors.
People also search for: dog nasal tumor treatment · radiation therapy for dogs · canine nasal cancer survival rate
Abstract
The object of this study was to evaluate hypofractionated multiportal field and two-portion (rostral and caudal portions divided by the eyelid) radiation therapy for canine nasal tumors. Sixty-three dogs underwent multiportal hypofractionated radiation therapy. The radiation field was divided into rostral and caudal portions by the eyelid. Treatments were performed four times for 57 dogs. The median irradiation dose/fraction was 8 Gy (range, 5-10 Gy); the median total dose was 32 Gy (10-40 Gy). Improvement of clinical symptoms was achieved in 53 (84.1%) of 63 cases. Median survival time was 197 days (range, 2-1,080 days). Median survival times with and without destruction of the cribriform plate before radiotherapy were 163 and 219 days, respectively. There was no significant difference between them. No other factors were related to survival according to a univariate analysis. All radiation side effects, except one, were grade I according to the VRTOG classification. It was not necessary to treat any dogs for skin side effects. One dog (1.6%) developed an oronasal fistula 1 year after completion of radiation therapy. This radiation protocol may be useful in reducing radiation side effects in dogs with cribriform plate destruction.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20938105/