Peer-reviewed veterinary case report
Ocular infections in cats and dogs caused by Encephalitozoon cuniculi
By Hofmann-Wellenhof, Sophie & Nell, Barbara·Published in Veterinary ophthalmology·2025·Department for Companion Animals and Horses·View original on PubMed →
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Original publication title: Retrospective study on Encephalitozoon cuniculi infections in 118 cat and 9 dog eyes.
Plain-English summary
A 5-year-old mixed-breed dog was diagnosed with cataracts and inflammation in the eye due to an infection called Encephalitozoon cuniculi. The vet confirmed the diagnosis through blood tests and analysis of the eye lens. Treatment involved surgery to remove the cataracts, along with anti-inflammatory and antiparasitic medications. After the procedure, the dog showed improvement, suggesting that this combination of treatments can be effective for managing eye problems caused by this infection.
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Abstract
PURPOSE: This study aims to inform about the clinical image, diagnostic possibilities, and treatment options for cats and dogs diagnosed with ocular encephalitozoonosis. MATERIALS AND METHODS: Medical records of 7 dogs and 75 cats with ocular encephalitozoonosis presented at the Clinical Unit of Ophthalmology of the University of Veterinary Medicine Vienna between 08/2006 and 02/2022 have been compiled. Diagnosis was based on the presence of cataracts and positive antibody titer against Encephalitozoon cuniculi. Patient history, details on the characteristics of the cataracts, level of antibody titers, and the treatment regimen were summarized, as are the results of histological stainings of surgical samples to determine the presence of Encephalitozoon cuniculi, as well as PCR analyses to identify its sub-strains. RESULTS: Our analysis of the clinical data shows that focal cortical anterior cataracts often associated with anterior uveitis and lesions in the fundus are the most prevalent manifestation of ocular encephalitozoonosis in cats and dogs. CONCLUSION: Serological testing and PCR analysis of lens material are the most important diagnostic tools. Timely phacoemulsification with adjuvant anti-inflammatory and antiparasitic medication is the most promising therapy for Encephalitozoon cuniculi-induced cataracts.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39610030/