Peer-reviewed veterinary case report
Dog's severe pulmonary hypertension heart changes reversed
By McMahon P & Saelinger C·Published in Veterinary Medicine: Research and Reports·2015
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Original publication title: Reversal of echocardiographic right-sided heart pathology in a dog with severe pulmonary hypertension: a case report
- Species:
- dog
Plain-English summary
A 7-year-old mixed-breed dog was diagnosed with severe pulmonary hypertension (PH) and showed signs of right-sided heart problems, including issues with the tricuspid valve. The veterinarian treated the dog with sildenafil, a medication that helps lower blood pressure in the lungs. After treatment, follow-up echocardiograms showed significant improvement in the dog's heart function, with reduced right heart strain and better overall heart health. This case highlights how effective treatment can lead to remarkable recovery in dogs suffering from severe PH.
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Abstract
Peggy McMahon,1 Carley Saelinger 2 1Emergency and Critical Care Department, 2Cardiology Department, Animal Specialty and Emergency Center, Los Angeles, CA, USA Abstract: Pathologic right-sided heart changes are a common echocardiographic finding in patients with pulmonary hypertension (PH). Canines with PH may have right heart pathology documented via echocardiographic color Doppler interrogation including tricuspid valve regurgitation, pulmonic valve insufficiency, elevated pulmonary arterial systolic pressure, elevated pulmonary arterial diastolic pressure, and alterations in ejection profiles. Two-dimensional echocardiographic findings may include right ventricular hypertrophy, interventricular septal flattening, paradoxical interventricular septal motion, pulmonary artery dilation, and potentially abnormal left heart dimensions. In veterinary medicine, much confidence is given to the measurement of pulmonary arterial systolic pressure estimated from tricuspid valve regurgitation to grade the severity of PH and monitor its improvement with little emphasis placed on the integration of two-dimensional echocardiographic right and left heart pathology in conjunction with Doppler findings. To the authors’ knowledge, marked improvement and/or resolution of echocardiographic-documented right heart pathology have not been previously reported in the veterinary literature. This case report documents profound echocardiographic improvement of right-sided heart disease in a dog with severe PH. Keywords: canine, pulmonary hypertension, tricuspid valve regurgitation, right heart hypertrophy, sildenafil
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