Peer-reviewed veterinary case report
Review of cobalamin status and disorders of cobalamin metabolism in dogs.
- Journal:
- Journal of veterinary internal medicine
- Year:
- 2020
- Authors:
- Kather, Stefanie et al.
- Affiliation:
- Department for Small Animals · Germany
- Species:
- dog
Abstract
Disorders of cobalamin (vitamin B) metabolism are increasingly recognized in small animal medicine and have a variety of causes ranging from chronic gastrointestinal disease to hereditary defects in cobalamin metabolism. Measurement of serum cobalamin concentration, often in combination with serum folate concentration, is routinely performed as a diagnostic test in clinical practice. While the detection of hypocobalaminemia has therapeutic implications, interpretation of cobalamin status in dogs can be challenging. The aim of this review is to define hypocobalaminemia and cobalamin deficiency, normocobalaminemia, and hypercobalaminemia in dogs, describe known cobalamin deficiency states, breed predispositions in dogs, discuss the different biomarkers of importance for evaluating cobalamin status in dogs, and discuss the management of dogs with hypocobalaminemia.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31758868/