Peer-reviewed veterinary case report
Rabbit with leg tumor causing fracture and amputation
By Kopp, Logan et al.·Published in Topics in companion animal medicine·2024·Priest Lake Veterinary Hospital, United States·View original on PubMed →
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Original publication title: Rhabdomyosarcoma in a Rabbit.
- Species:
- rabbit
Plain-English summary
A geriatric Holland Lop rabbit was brought in for sudden lameness and was found to have a broken leg due to a type of cancer called rhabdomyosarcoma. The vet amputated the affected leg, and tests confirmed the diagnosis. Unfortunately, the rabbit passed away about a year later, and a follow-up examination revealed that the cancer had spread to several other organs.
People also search for: rabbit lameness · Holland Lop cancer symptoms · rabbit leg amputation recovery
Abstract
A geriatric Holland Lop rabbit presented for acute lameness. A pathologic fracture of the right distal femur associated with a pleomorphic rhabdomyosarcoma was diagnosed, and staging radiographs showed no overt metastasis upon initial presentation. The limb was amputated and submitted for microscopic examination. Immunohistochemical evaluation revealed the neoplastic cells were positive for desmin and MyoD1, and negative for cytokeratin AE1/AE3, CD204, IBA-1, and SMA. Gross, histologic, and immunohistochemical evaluation confirmed a diagnosis of pleomorphic rhabdomyosarcoma. The patient died 396 days after amputation, and a post-mortem examination showed metastatic sarcoma to multiple organs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38972503/