Peer-reviewed veterinary case report
Right heart function in dogs with mitral valve disease
By Yuchi, Yunosuke et al.·Published in The Journal of veterinary medical science·2021·School of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Right ventricular systolic and diastolic function assessed by two-dimensional speckle tracking echocardiography in dogs with myxomatous mitral valve disease.
- Species:
- dog
Plain-English summary
A group of dogs with myxomatous mitral valve disease (MMVD) were studied to see how pulmonary hypertension (PH) affected their heart function. The research found that dogs with a high likelihood of PH had worse right heart function compared to those with lower probabilities. Specifically, their heart's ability to pump blood and fill properly was significantly impaired. This suggests that if your dog has MMVD and shows signs of heart problems, it may be worth discussing the possibility of PH with your veterinarian, as it can lead to more serious heart issues.
People also search for: dog heart problems MMVD · pulmonary hypertension in dogs · myxomatous mitral valve disease treatment
Abstract
Pulmonary hypertension (PH) is a common comorbidity in dogs with myxomatous mitral valve disease (MMVD), and can induce various changes in the right heart, such as right ventricular (RV) hypertrophy, dilatation, and dysfunction. We hypothesized that RV function, not only systolic function but also diastolic function, could be worsened with PH progression. We aimed to compare RV systolic and diastolic function in dogs with MMVD. Twenty healthy dogs and sixty-eight dogs with MMVD were enrolled. Dogs with MMVD were classified into the probability of PH. Two-dimensional and Doppler echocardiographic indices for right heart and two-dimensional speckle tracking echocardiography indices were measured. The morphological indicators of the right heart were significantly higher only in the high probability of PH group. The RV strain, early-diastolic and systolic strain rates were significantly lower in the high probability of PH group than those in the low and intermediate probability of PH groups. Multivariate analysis showed that increased RV internal dimension normalized by body weight and RV myocardial performance index were significantly associated with the presence of right-sided congestive heart failure. Speckle tracking echocardiography-derived RV systolic and diastolic function were activated in the low and intermediate probability of PH groups. However, dogs with high probability of PH showed RV myocardial dysfunction and dilatation. Increased RV myocardial performance index and end-diastolic RV internal dimension normalized by body weight were significantly associated with the presence of right-sided congestive heart failure in dogs with MMVD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34732606/