Peer-reviewed veterinary case report
Gastric cancer signs and risk in chow chow dogs
By Koterbay, Amy M et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2020·University College Dublin, United States·View original on PubMed →
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Original publication title: Risk and characteristics of gastric carcinoma in the chow chow dog.
- Species:
- dog
Plain-English summary
A group of chow chow dogs showed signs of gastric carcinoma, which is a type of stomach cancer, typically presenting with symptoms like vomiting, loss of appetite, diarrhea, and dark stools. Most of these dogs were diagnosed about three weeks after symptoms began and were euthanized within two weeks of diagnosis without treatment. However, two dogs that received aggressive treatment, including surgery and chemotherapy, managed to survive for 12 and 36 months. This highlights the importance of early detection and treatment for better outcomes in affected dogs.
People also search for: chow chow vomiting · dog stomach cancer treatment · signs of cancer in dogs
Abstract
Gastric carcinoma is not commonly reported in dogs. There is an increased risk, however, in certain breeds such as the Belgian Tervuren. Review of the Veterinary Medical Database (VMDB) established an increase in risk for gastric carcinoma in the chow chow breed. In 106 chow chow dogs signs commenced, on average, 3 weeks before definitive diagnosis. The most common clinical signs were vomiting, loss of appetite, diarrhea, and melena. Most affected dogs were euthanized, without treatment, within 2 weeks of diagnosis. Two dogs which were treated aggressively (surgery and chemotherapy) survived a considerably longer time (12 and 36 months). Histologically, these chow chow dogs comprised a similar histologic type as familial gastric carcinoma in humans; diffuse-type carcinoma that was enriched in the signet ring and mucinous variants. Understanding the pathogenesis of diffuse gastric carcinoma in the chow chow dog may provide insight into the biology of this aggressive cancer in humans.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32255825/