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Peer-reviewed veterinary case report

Risk factors for Candida urinary infections in dogs and cats

By Reagan, Krystle L et al.·Published in Journal of veterinary internal medicine·2019·William R. Pritchard Veterinary Medical Teaching Hospital, United States·View original on PubMed

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Original publication title: Risk factors for Candida urinary tract infections in dogs and cats.

Species:
dog
Drinking & peeingDogs

Plain-English summary

A group of 18 dogs and 8 cats with urinary tract infections caused by Candida were studied to find out what might have led to these infections. It was found that recent use of antibacterial medications was a significant risk factor for both dogs and cats, increasing the chances of developing candiduria (Candida in the urine). Additionally, dogs with weakened immune systems and cats with other urinary tract issues were also more likely to have these infections. The findings suggest that careful use of antibiotics could help prevent these types of infections in pets.

People also search for: dog urinary tract infection treatment · cat Candida infection symptoms · antibiotics and urinary tract infections in pets

Abstract

BACKGROUND: Candida urinary tract infections occur in both dogs in cats but there is limited data about risk factors. OBJECTIVE: To identify risk factors for candiduria in dogs in cats. ANIMALS: Eighteen dogs and 8 cats with candiduria. METHODS: A retrospective case-control study, using univariate exact logistic regression. Medical records were searched for a diagnosis of Candida and animals with culture-confirmed candiduria were enrolled. Controls had bacterial cystitis (dogs and cats) or cutaneous Malassezia infection (dogs only). RESULTS: Administration of antibacterial drugs in the 30 days before diagnosis was associated with candiduria in dogs compared to controls with bacterial cystitis (OR 14.5; 95% CI 3.1-66.9) or with Malassezia infection (OR 26.4; 95% CI 3.4-206.7). Antecedent antibacterial drug administration was associated with candiduria in cats (OR 15.7; 95% CI 1.9-132.3). Immunosuppression was associated with candiduria in dogs when compared to controls with Malassezia infection (OR 4.2, 95% CI 1.4-12.8), but not significantly when compared to dogs with bacterial cystitis (OR 2.7, 95% CI 0.9-8.0). Lower urinary tract diseases other than infection were associated with candiduria in cats (OR 6.7, 95% CI 1.6-27.9), but not significantly in dogs (OR 2.5, 95% CI 0.7-8.7). Neither diabetes mellitus nor history of hospitalization was significantly associated with candiduria in either species. CONCLUSIONS AND CLINICAL IMPORTANCE: The recent administration of antibacterial drug therapy is a potential risk factor for development of candiduria in dogs and cats. Judicious use of antibacterial drugs might help to prevent candiduria.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30758081/