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Peer-reviewed veterinary case report

Rodent-free cyclical transmission of Trypanosoma brucei brucei.

Journal:
Molecular and biochemical parasitology
Year:
2017
Authors:
Naguleswaran, Arunasalam & Roditi, Isabel
Affiliation:
Institute of Cell Biology

Abstract

We provide a simple protocol enabling cyclical transmission of Trypanosoma brucei brucei to be performed without the need for mammals. These procedures have two advantages: they are in line with 3R principles of animal use - replace, refine, reduce - and may enable more laboratories to study the complete life cycle.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28843782/