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Peer-reviewed veterinary case report

Role of beta-hydroxybutyric acid in diabetic ketoacidosis: a review.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2011
Authors:
Stojanovic, Vladimir & Ihle, Sherri
Affiliation:
Department of Companion Animals

Plain-English summary

Diabetic ketoacidosis (DKA) is a serious condition that can happen in pets with diabetes, and it often needs urgent care. It can be tricky to diagnose because the signs can vary from one pet to another. This article looks at how certain acids, specifically beta-hydroxybutyric acid, are formed during DKA and how they can help in diagnosing and keeping track of the condition. Understanding these details is important for providing the right treatment for pets suffering from DKA.

Abstract

Diabetic ketoacidosis (DKA), a complication of diabetes mellitus, is a severe metabolic disease that often requires intensive treatment. Diagnosis of ketosis associated with DKA can be difficult due to variability in the metabolic state of DKA patients. Recognition of the clinical signs and definitive diagnosis are essential for proper treatment. This article reviews the formation of ketoacids during DKA and the role of β-hydroxybutyric acid in the diagnosis and monitoring of DKA.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21731100/