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Peer-reviewed veterinary case report

Role of statins in cerebral vasospasm.

Journal:
Acta neurochirurgica. Supplement
Year:
2008
Authors:
Sugawara, T et al.
Affiliation:
Department of Physiology and Pharmacology · United States

Abstract

3-Hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors, commonly known as statins, are widely used clinically for their lipid lowering properties. Recent evidence shows that statins are also effective in ameliorating cerebral vasospasm, which occurs as sequelae of subarachnoid haemorrhage. This review focuses on the pleiotropic effects of statins, and the putative mechanisms involved in statin mediated attenuation of cerebral vasospasm.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18457003/