Peer-reviewed veterinary case report
Room temperature, metal-free, CDI-promoted, ex-situ protocol for S-methyl thioester synthesis.
- Year:
- 2025
- Authors:
- Patel MA et al.
- Affiliation:
- Department of Chemistry · India
Abstract
S-methyl thioesters have proven to be useful intermediates in many biosynthetic reactions and their occurrence in bioactive molecules further enhance their appeal. Shortcomings in several reported synthetic protocols have led us to disclose herewith a mild, room temperature ex situ protocol that provides access to a large number of thioesters (aryl, heteroaryl, alkyl, amino acids). Late-stage functionalization strategies were also performed on commercial pharmaceutical drugs (containing carboxylic acid functionality) while further in situ conversion to valuable compounds has also been achieved.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://europepmc.org/article/MED/40425747