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Peer-reviewed veterinary case report

Safe and effective mouse footpad inoculation.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2013
Authors:
Long, Kristin M & Heise, Mark
Affiliation:
Department of Genetics · United States
Species:
rodent

Abstract

Footpad injection is an important route of inoculation in mouse models of disease and immunology. Although commonly used to deliver antigens as a means of eliciting an efficacious immunological response, herein, we describe a protocol for inoculating mice via footpad injection using a hands-free method to deliver infectious material. These procedures allow for efficient delivery of infectious agents in a manner that is safe for both the researcher and animal.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23824892/