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Peer-reviewed veterinary case report

Tuberculosis vaccine safe in cats with feline immunodeficiency virus

By Zimmerman, Dawn M et al.·Published in Clinical and vaccine immunology : CVI·2009·Memphis Zoo and Aquarium, United States·View original on PubMed

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Original publication title: Safety and immunogenicity of the Mycobacterium tuberculosis DeltalysA DeltapanCD vaccine in domestic cats infected with feline immunodeficiency virus.

Species:
cat

Plain-English summary

Four domestic cats, some infected with feline immunodeficiency virus (FIV) and some not, received a new vaccine designed to help protect against tuberculosis. The vaccine triggered an immune response, but the response was weaker in the FIV-positive cats compared to those without the virus. Fortunately, there were no serious side effects noted in any of the cats after vaccination. This suggests that the vaccine is safe for use in both FIV-positive and FIV-negative cats.

People also search for: cat tuberculosis vaccine · FIV positive cat treatment · feline immunodeficiency virus vaccine safety

Abstract

Feline immunodeficiency virus (FIV)-positive and FIV-negative cats (n=4/group) received 2 x 10(6) CFU Mycobacterium tuberculosis DeltalysA DeltapanCD intramuscularly. Vaccination elicited antibody responses, albeit at lower levels in FIV-positive cats than in FIV-negative cats. Delayed-type hypersensitivity responses were minimal in both groups. No adverse reactions were found.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19144788/