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Peer-reviewed veterinary case report

Safety of giving cats fluralaner with emodepsid-praziquantel together

By Walther, Feli M et al.·Published in Parasites & vectors·2016·Merck Animal Health, United States·View original on PubMed

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Original publication title: Safety of concurrent treatment of cats with fluralaner and emodepsid-praziquantel.

Species:
cat

Plain-English summary

A study looked at the safety of treating cats with both fluralaner, which helps control fleas and ticks, and a combination of emodepsid and praziquantel, which treats intestinal worms. Some cats showed mild reactions like redness at the application site, and a few had slight salivation or vomiting, but these were temporary and expected. Overall, the combination treatment was well tolerated without any serious safety concerns.

People also search for: cat flea and tick treatment · cat worm treatment · fluralaner safety for cats

Abstract

BACKGROUND: Fluralaner is a novel systemic ectoparasiticide for cats providing immediate and persistent flea- and tick-control after a single topical dose. Emodepsid and praziquantel are routinely used to control intestinal worm infections in cats. The safety of concurrent use of fluralaner and a commercially available emodepsid-praziquantel combination topical solution was investigated using topical administrations at the maximum recommended dose rates. FINDINGS: Few mild and transient clinical findings like erythema at the administration site and single incidences of salivation or vomiting were observed. All of which were consistent with the individual product leaflets. There were no findings suggesting an increased safety risk associated with the concurrent treatment of cats with fluralaner and emodepsid-praziquantel. CONCLUSIONS: Concurrent treatment with fluralaner, emodepsid and praziquantel is well tolerated in cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27267592/