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Peer-reviewed veterinary case report

Safety of contrast ultrasound in dogs and cats from 2002 to 2011

By Seiler, Gabriela S et al.·Published in Journal of the American Veterinary Medical Association·2013·Department of Molecular Biomedical Science, United States·View original on PubMed

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Original publication title: Safety of contrast-enhanced ultrasonography in dogs and cats: 488 cases (2002-2011).

Stomach & digestion

Plain-English summary

A study looked at the safety of a special imaging test called contrast-enhanced ultrasonography (CEUS) in dogs and cats. Out of 750 animals, only a few experienced minor issues like vomiting right after the test, and no problems were reported in cats. The researchers found that the risk of death within 24 hours was similar for animals that had CEUS and those that had regular ultrasonography without the contrast agent. Overall, the findings suggest that CEUS is a safe option for diagnosing health issues in pets.

People also search for: dog vomiting after ultrasound · cat ultrasound safety · pet imaging test risks

Abstract

OBJECTIVE: To determine the incidence of adverse events within 24 hours after contrast-enhanced ultrasonography (CEUS) in dogs and cats and compare the risk of death within 24 hours after imaging for animals that underwent ultrasonography with and without injection of a contrast agent. DESIGN: Retrospective case-control study. ANIMALS: 750 animals (411 case dogs, 238 control dogs, 77 case cats, and 24 control cats). PROCEDURES: At 11 institutions, medical records were reviewed of dogs and cats that had CEUS performed (cases) as were medical records of dogs and cats with clinical signs similar to those of case animals that had ultrasonography performed without injection of a contrast agent (controls). Information regarding signalment; preexisting disease; type, dose, and administration route of contrast agent used; immediate (within 1 hour after CEUS) and delayed (> 1 and ≤ 24 hours after CEUS) adverse events; and occurrence and cause of death (when available) was extracted from each medical record. Risk of death within 24 hours after ultrasonography was compared between case and control animals. RESULTS: Of the 411 case dogs, 3 had immediate adverse events (vomiting or syncope) and 1 had a delayed adverse event (vomiting). No adverse events were recorded for case cats. Twenty-three of 357 (6.4%) clinically ill case animals and 14 of 262 (5.3%) clinically ill control animals died within 24 hours after ultrasonography; risk of death did not differ between cases and controls. CONCLUSIONS AND CLINICAL RELEVANCE: Results indicated that CEUS was safe in dogs and cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23600783/