Peer-reviewed veterinary case report
Safety of giving fluralaner plus moxidectin with praziquantel on cats
By Walther, Feli M et al.·Published in Parasites & vectors·2018·Merck Animal Health, United States·View original on PubMed →
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Original publication title: Safety of topical administration of fluralaner plus moxidectin concurrently with praziquantel in cats.
- Species:
- cat
Plain-English summary
Ten cats were treated with a topical solution that combined fluralaner and moxidectin, along with another topical treatment for tapeworms called praziquantel. The treatments were given at the highest recommended doses, and the cats did not show any serious side effects. A few cats developed some minor skin flakes or small bits of material at the application site, but these were not concerning. Overall, the combination treatment was safe and well tolerated by the cats.
People also search for: cat flea and worm treatment · fluralaner moxidectin safety · praziquantel for cats side effects
Abstract
BACKGROUND: Fluralaner provides efficacy against feline ectoparasites following topical administration. Moxidectin is routinely used to treat gastrointestinal nematode infections and prevent heartworm disease caused by Dirofilaria immitis. Praziquantel is routinely used to treat feline tapeworm infections. The safety of a fluralaner plus moxidectin combination topical solution (Bravecto™ Plus, MSD Animal Health) was assessed when administered concurrently with a commercially available praziquantel topical solution (Droncit™ Spot-on, Bayer Animal Health GmbH). The highest dose rates in clinical use were tested. RESULTS: Concurrent topical administration of a fluralaner plus moxidectin and a praziquantel product did not result in adverse findings. One out of ten cats receiving praziquantel only (control group), and two out of ten cats receiving fluralaner plus moxidectin and praziquantel (treatment group) had dandruff-like flakes in their coat at the application site. Two out of the ten control cats and three cats out of the ten treatment group cats had very small amounts of unidentified material (minute crusts or crumbs) at the application site which was only visible during close inspection. CONCLUSIONS: The concurrent treatment of cats with fluralaner plus moxidectin and praziquantel at the maximum dose in clinical use was well tolerated.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30454033/