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Peer-reviewed veterinary case report

Signs of salinomycin poisoning in horses

By Rollinson, J et al.·Published in The Veterinary record·1987·School of Veterinary Science, United Kingdom·View original on PubMed

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Original publication title: Salinomycin poisoning in horses.

Species:
horse
Colic in horsesStomach & digestionHorses

Plain-English summary

This study looked at six horses that accidentally ate feed contaminated with salinomycin, a substance that can be toxic to them. The horses showed a variety of symptoms, including not eating, belly pain, weakness, and difficulty walking. Their blood tests also showed changes similar to those seen in horses poisoned by a related substance called monensin. Although poisoning from these substances is not commonly reported in horses, it’s important for veterinarians to consider it when horses show digestive issues or trouble moving, especially if they are around feed used for other animals. The study highlights the need for caution with certain types of feed that could harm horses.

Abstract

Six cases of accidental salinomycin poisoning in horses are described. The horses were fed a contaminated ration and presented clinical signs which were extremely varied in nature and severity. However, the range of signs, including anorexia, colic, weakness and ataxia bore similarities to those described in horses poisoned with the related ionophore monensin. Other similarities became apparent in serum biochemical profiles of the clinical cases. Although ionophore toxicity is rarely reported in horses they appear to be particularly susceptible, and it should therefore be considered as a differential diagnosis of digestive upsets or locomotory disorders at establishments where ionophore-treated feeds are used therapeutically in other species.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/3672848/