Peer-reviewed veterinary case report
Dog with salivary gland cancer showing high-grade changes
By Kishimoto, T E et al.·Published in Journal of comparative pathology·2015·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Salivary Gland Epithelial-Myoepithelial Carcinoma with High-Grade Transformation in a Dog.
- Species:
- dog
Plain-English summary
An 8-year-old male neutered standard dachshund was brought to the vet because of a slowly growing lump in his left jaw area, near the salivary gland. After examining the mass, the vet found it was a type of tumor called epithelial-myoepithelial carcinoma, which had some aggressive features. The dog underwent surgery to remove the tumor, and thankfully, there were no signs of it coming back or spreading to other parts of the body even 18 months later. The dog is doing well after the treatment.
People also search for: dog salivary gland tumor · dachshund jaw lump · epithelial-myoepithelial carcinoma treatment
Abstract
An 8-year-old male neutered standard dachshund was presented with a slowly growing mass in the left submandibular salivary gland. Histopathological examination revealed a tumour that was composed of bilayered duct-like structures with an inner layer of ductal cells and an outer layer of clear cells. Both inner and outer cells in the greater part of the tumour exhibited low to moderate atypia and low mitotic activity. However, a focal area towards the periphery showed enhanced cellular atypia and mitotic activity in tumour cells. Immunohistochemically, the outer layer of clear cells expressed myoepithelial markers, while the inner layer cells were positive for a luminal epithelial marker. No local recurrence or lymph node or distant metastasis was observed 18 months following surgery. Based on the morphology and immunohistochemical findings, a final diagnosis of epithelial-myoepithelial carcinoma with high-grade transformation was made.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26223938/