Peer-reviewed veterinary case report
Salmonella flagellin is not a dominant protective antigen in oral immunization with attenuated live vaccine strains.
- Journal:
- Infection and immunity
- Year:
- 2004
- Authors:
- Kodama, Chie & Matsui, Hidenori
- Affiliation:
- Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences · Japan
- Species:
- rodent
Abstract
We found that oral immunization with flagellum-defective mutant strains of Salmonella enterica serovar Typhimurium with the ClpXP-deficient background protected mice against oral challenge with the virulent strain. These data indicate that Salmonella flagellin is not a dominant protective antigen in oral immunization with attenuated live vaccine strains.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15039380/