Peer-reviewed veterinary case report
Dog with bone infection from Scedosporium inflatum mold
By Salkin, I F et al.·Published in Journal of clinical microbiology·1992·New York State Department of Health, United States·View original on PubMed →
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Original publication title: Scedosporium inflatum osteomyelitis in a dog.
- Species:
- dog
Plain-English summary
A 6-year-old spayed female beagle suddenly developed lameness in her right front leg. X-rays showed changes in the bone, and a biopsy revealed a fungal infection caused by Scedosporium inflatum. Despite being treated with an antifungal medication called itraconazole, the dog did not get better and was ultimately euthanized. An autopsy showed that the infection had spread to her lungs.
People also search for: dog lameness treatment · beagle fungal infection · Scedosporium inflatum in dogs · osteomyelitis in dogs · dog euthanasia reasons
Abstract
Scedosporium inflatum Malloch et Salkin was found to cause osteomyelitis in a 6-year-old spayed female beagle. The previously healthy dog suddenly developed right-forelimb lameness. Bony changes consisting of proliferation with some lysis were noted on radiographic examinations. Microscopic observations of stained sections of tissue obtained by biopsy of the distal humerus revealed the presence of septate branching hyphae. Cultures inoculated with tissue from a later biopsy yielded a mold subsequently identified as S. inflatum. Tissue sections stained with specific Scedosporium fluorescent-antibody conjugate were positive, further substantiating the diagnosis. Although the dog was treated with oral itraconazole, no improvement in the animal's condition was noted, and it was euthanized. Autopsy revealed dissemination of the etiologic agent to the lungs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1452649/