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Peer-reviewed veterinary case report

Fungal sinus infection by Scopulariopsis in a dog treated successfully

By Sri-Jayantha, Loren et al.·Published in Journal of the American Animal Hospital Association·2019·From the Department of Clinical Sciences (V.S.·View original on PubMed

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Original publication title: Scopulariopsis brevicaulis Rhinosinal Infection in a Dog.

Species:
dog
Breathing & coughDogs

Plain-English summary

A 1-year-old male American Staffordshire terrier mix was brought in for chronic nasal issues and was found to have a fungal infection called Scopulariopsis brevicaulis in his sinuses. The vet performed surgery to open the sinuses and used a special antibiotic gel during the procedure, followed by additional medication after surgery. Once the fungal infection was confirmed, the dog was treated with a systemic antifungal medication called terbinafine. Thankfully, he recovered well and has shown no signs of the infection returning for three years.

People also search for: dog nasal infection treatment · American Staffordshire terrier sinus problems · fungal infection in dogs

Abstract

A 1 yr old castrated male American Staffordshire terrier mix was treated for Scopulariopsis brevicaulis that was discovered during an evaluation of chronic rhinosinusitis. A sinusotomy was performed, with intraoperative infusion of amikacin-impregnated gel and systemic administration of postoperative amikacin. Antibiotic therapy was initially chosen because of historic culture of Mycoplasma. Fungal culture of the frontal sinus identified S. brevicaulis by combined phenotypic characterization and DNA sequencing after morphologic analysis failed to identify the organism. Systemic terbinafine therapy was instituted after fungal culture results were available. The patient recovered well and has had no clinical relapse of disease 3 yr after treatment. This is the first reported case of a fungal rhinosinusitis caused by S. brevicaulis in a dog. Reports of Scopulariopsis infections in humans indicate that treatment of S. brevicaulis infection is hampered by multidrug resistance; prognosis may be poor in people with invasive infections and is currently unknown in dogs. Multimodal therapy, including concurrent surgical and systemic intervention, may be necessary to optimize treatment success.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30427708/