Peer-reviewed veterinary case report
Scoring Sepsis Severity in Mice.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2021
- Authors:
- Mele, Tina S
- Affiliation:
- Department of Surgery · United Kingdom
- Species:
- rodent
Abstract
A reliable scoring system that predicts the development of sepsis, septic shock, and death enables comparison of disease severity and treatment outcomes in animal models of sepsis. Mice are used in the majority of preclinical sepsis studies. We describe a murine sepsis score that evaluates seven clinical variables in an experimental mouse model of polymicrobial sepsis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/34048014/