Peer-reviewed veterinary case report
Seasonal changes in acute phase response in dogs with Babesia canis
By Janjić, Filip et al.·Published in International journal of biometeorology·2022·Faculty of Veterinary Medicine·View original on PubMed →
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Original publication title: Seasonal differences in the intensity of acute phase response in dogs infected with Babesia canis.
- Species:
- dog
Plain-English summary
A group of dogs infected with Babesia canis, a disease spread by ticks, showed more severe symptoms during the peak tick season from February to May. Researchers found that during this time, dogs had lower levels of certain blood components and higher indicators of an intense immune response. This suggests that if your dog gets infected with Babesia canis during these months, they may experience a more serious illness. It's important to monitor your dog for symptoms like fever, lethargy, or loss of appetite during this period and consult your veterinarian for appropriate testing and treatment.
People also search for: dog Babesia canis symptoms · tick disease in dogs · how to treat Babesia canis in dogs
Abstract
The highest number of acute Babesia canis cases in dogs is recorded over the February-May (Feb-May) period, which also represents the optimal climate conditions for tick activity in Belgrade, Serbia. A possibility that the acute phase response is more intense in dogs developing the disease in the Feb-May period compared with the response in other time periods of the year was tested. A total of 63 client-owned dogs with acute B. canis infection were enrolled and the routine hematology and biochemistry parameters-serum amyloid A (SAA), IgG against B. canis, level of parasitemia, ceruloplasmin (CER), paraoxonase-1 (PON-1), and fibrinogen-were measured. Acute phase indexes (API) were calculated as (SAA×CER)/(Iron×PON-1) and (SAA×CER)/(Albumin×Iron). Statistics included Kruskal-Wallis test and logistic regression analysis. The results showed that in the Feb-May period, the following parameters were lower: creatinine, albumin, iron, and level of parasitemia. Furthermore, increased API values were more probable in the Feb-May than in the other periods. Together, higher acute phase response intensity and presumptive hemodilution in the Feb-May period indicate a more acute course of B. canis infection than in other time periods of the year.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34997356/