Peer-reviewed veterinary case report
Sebaceous adenitis causing hair loss in Akita dogs and its heredity
By Reichler, I M et al.Ā·Published in Veterinary dermatologyĀ·2001Ā·Department of ReproductionĀ·View original on PubMed ā
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Original publication title: Sebaceous adenitis in the Akita: clinical observations, histopathology and heredity.
- Species:
- dog
Plain-English summary
A group of 97 pure-bred Akitas was examined for sebaceous adenitis, a skin condition that leads to hair loss and inflammation of the sebaceous glands. In 23 of these dogs, vets confirmed the diagnosis by observing inflammation targeting the glands. The first signs typically appeared on the back and ears, with hair loss primarily affecting the undercoat. While the severity of the condition varied among dogs, some showed signs of regeneration of the sebaceous glands. This condition may have a genetic component, and immune system factors could also play a role in its development.
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Abstract
Ninety-seven pure-bred Akitas were examined clinically and histologically for sebaceous adenitis. The diagnosis was established histologically in 23 Akitas by demonstrating an inflammatory reaction targeted against the sebaceous glands or a reduction in the number of glands. The clinical course of sebaceous adenitis in the Akita was similar to that seen in other breeds. The first skin lesions occurred mainly on the dorsal midline and ears. Compared with the Poodle, the age at first onset of the disease was more variable and the hair loss affected mainly the undercoat. The progression of sebaceous gland destruction varied between dogs and was not seen in all cases. Because bud-like sebaceous gland proliferation could be identified, it seems that regeneration of the sebaceous glands may occur. An autosomal recessive inheritance appears to be possible. Apart from a genetic background, immune-mediated factors possibly influence the onset and course of sebaceous adenitis.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11906649/