Peer-reviewed veterinary case report
Right atrial blood clots in dogs treated with clopidogrel
By Yoshida, Tomohiko et al.·Published in Veterinary medicine and science·2023·Department of Clinical Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Secondary right atrial thrombosis in three dogs: Antithrombotics therapy and echocardiographic follow-up.
- Species:
- dog
Plain-English summary
Three dogs were diagnosed with blood clots in the right side of their hearts, which were likely caused by other health issues like Cushing's disease or pancreatitis. The clots were confirmed through ultrasound and were treated with a combination of two medications, clopidogrel and rivaroxaban. After starting this treatment, the clots gradually disappeared, and all three dogs showed complete recovery. This treatment was found to be safe and well-tolerated, allowing for effective management of their condition.
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Abstract
Three dogs were diagnosed with right atrial thrombosis, thought to be secondary to systemic diseases. Specifically, two cases had hyperadrenocorticism and one case was diagnosed with pancreatitis with acute renal injury. In all cases, the thrombi were found within the right atrium, necessitating a differentiation from cardiac neoplasia. In all three cases, the structures assumed to be thrombi had irregular margins with interspersed hypoechoic regions, which were later confirmed as thrombi based on the responsiveness to therapy. All three cases were prescribed with the combination of clopidogrel and rivaroxaban.The thrombi gradually disappeared after initiation of the combination therapy. Complete resolution of right atrial thrombosis was noted in each dog treated with clopidogrel and rivaroxaban. This combination therapy appears to be safe and well tolerated. Diligent observation of the echocardiographic findings and clinical course allows the diagnosis of thrombosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37491011/