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Peer-reviewed veterinary case report

Secretion of Thioredoxin Peroxidase Protein of Cat Liver Fluke Opisthorchis felineus during Modeling of Experimental Opisthorchiasis.

Journal:
Bulletin of experimental biology and medicine
Year:
2017
Authors:
Petrenko, V A et al.
Affiliation:
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences

Abstract

Mechanisms of thioredoxin peroxidase secretion by Opisthorchis felineus were studied in vivo and in vitro. Specific antibodies were obtained and used for western blotting and immunohistochemical detection in Syrian hamster model of opisthorchiasis. Secreted thioredoxin peroxidase protein was accumulated in the worm incubation medium under conditions of oxidative stress and in bile duct cells of hamsters with chronic opisthorchiasis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28429227/