Peer-reviewed veterinary case report
How well blood tests detect pancreatitis in dogs with visible
By Steiner, Jorg M et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2008·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Sensitivity of serum markers for pancreatitis in dogs with macroscopic evidence of pancreatitis.
- Species:
- dog
Plain-English summary
A group of dogs diagnosed with pancreatitis (inflammation of the pancreas) was tested to see how well new blood tests could identify the condition. The tests measured specific proteins related to pancreatitis and were found to be very effective in detecting the disease in dogs that showed clear signs of it. While these new tests showed high sensitivity, more research is needed to understand how specific they are and how they can be used in everyday veterinary practice.
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Abstract
Pancreatitis is recognized as an important and common problem in dogs, but diagnosis can be challenging. Recently, new assays for the measurement of trypsin-a1-proteinase inhibitor complexes and canine pancreatic lipase immunoreactivity (cPLI and Spec cPL) have been developed and analytically validated. This is the first report of a direct comparison of the sensitivity of these and other more traditional serum markers for the diagnosis of canine pancreatitis in a subset of dogs with this disease (i.e., dogs with both macroscopic and microscopic changes characteristic of pancreatitis). Serum cPLI and Spec cPL concentrations showed the highest sensitivity for the diagnosis of pancreatitis in this group of patients. Further studies will be required to compare the specificity of these serum markers and thus determine their overall clinical utility.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19177331/